Phthalate exposures in a Canadian birth cohort at three months of age: the CHILD study

Methods We employed the Canadian Healthy Infant Longitudinal Development (CHILD) Study, a multicentre, longitudinal, population-based birth cohort with 3,300 children to identify sources of phthalate exposures in infants. For the first 1,539 CHILD participants we examined associations between 6 urinary phthalate metabolites, measured at 3 months of age and corrected for specific gravity, with 90 variables characterizing the indoor environment, including furnishings, household care products and personal care products. Univariate, Bivariate, and Tobit regression were used for modeling. We also examined the relationship of urinary phthalates with socio-demographic characteristics and breastfeeding.